![]() In normal conditions, insulin binds to special receptors on the cell surfaces and initiates reactions involved in glucose metabolism.Insulin resistance occurs in diabetes mellitus, wherein there is a decrease in tissue sensitivity to insulin.Polyphagia and fatigue result from the break down of nutritional stores.Lack of insulin makes the body unable to use carbohydrates primarily and instead uses fats and proteins for energy production, resulting in ketosis and weight loss.Osmotic diuresis causes water loss, resulting in polydipsia.Blood being delivered in the kidneys has high glucose concentration causing osmotic diuresis and glycosuria.Glucose accumulates in the serum causing hyperglycemia.There is a destruction of the islet cells in the pancreas causing insufficient insulin and excess glucagon.Gestational diabetes mellitus is characterized by glucose intolerance of any degree that occurs during pregnancy.Commonly occurs in patients with obesity and those with genetic susceptibility to DM. Type 2 diabetes mellitus, formerly called non-insulin dependent diabetes mellitus, is characterized by defects in insulin release and use, and insulin resistance.Type 1 diabetes may result from an autoimmune process triggered by a virus Type 1 diabetes mellitus or, formerly called insulin-dependent diabetes mellitus, typically occurs in younger people with the exact cause is unknown.Sustained hyperglycemia has been shown to affect almost all tissues in the body and is associated with significant complications of multiple organ systems, including the eyes, nerves, kidneys, and blood vessels. ![]() ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |